Profile Summary & Research Vision

Dr. Mamathashree M. N. is an interdisciplinary molecular biologist specializing in translational genetics, macromolecular biochemistry, crop improvement, and immunoinformatics. Her established scientific trajectory focuses on integrating empirical wet-lab discoveries with predictive computational pipelines to decode complex genetic and biochemical architectures. At the Central Silk Board, her research aims to apply these core molecular principles toward advanced sericultural systems biology.

Her future research interests focus on dissecting organismal development by elucidating the molecular etiology, epigenetic modifications, and hormonal pathways regulating developmental anomalies and economic phenotypes in silkworms. Additionally, she aims to develop expertise in precision genome editing, embryonic microinjection modification systems, and endocrine profiling assays.

Core Competencies & Methodology

Genomics & Molecular Breeding

High-resolution molecular marker genotyping, population genetic architecture modeling, and high-throughput germplasm characterization.

Analytical Biochemistry

Metabolite profiling by HPLC, qualitative and quantitative biochemical assays, and nutritional characterization of germplasm.

Transcriptomics & Diagnostics

Functional gene expression profiling, nucleic acid-based diagnostics, and macromolecular interaction networks.

Computational Biology & Immunoinformatics

In silico multi-epitope vaccine architecture, molecular docking simulations, and phylogeographic mapping of high-consequence pathogens.

Academic & Professional Trajectory

Education

Ph.D. in Biotechnology & Crop Improvement
University of Horticultural Sciences (UGC Fellowship)
B.Sc. (Agri) & M.Sc. (Agri) in Plant Biotechnology
University of Agricultural Sciences

Professional Experience

Scientist B
Central Silk Board
Former Assistant Professor
Indian Institute of Packaging (IIP)
Senior Research Fellow
ICAR-NIVEDI (NICRA)

Awards & Recognitions

Best Researcher Award (2021)

ICFAI

Young Professional Award (2022)

Disha

Best Participant Award

Int. Conf. Green Tech for Health & Env

Best Oral Presentation Award

Int. Conf. on Decarbonizing Agriculture

Selected Publications

  1. Mamathashree, M. N., & Shyamalamma, S. (2022). Screening of bush type French bean (Phaseolus vulgaris L.) accessions for micronutrient variations and characterization of selected genotypes using micronutrient content linked markers. Legume Research, 45(3), 285-291.
  2. Mamathashree Mandya Naganayak, Puttahonnappa, S. K., Indrabalan, U. B., Paramanandham, K., Jacob, S. S., Subramaniam, S., & Goroshi, S. (2022). An extensive analysis of codon usage pattern, evolutionary rate, and phylogeographic reconstruction in Foot and Mouth Disease serotypes. Acta Tropica, 236, 106674.
  3. Swati Rani, M. N. Mamathashree, Uma Bharthi I., S. S. Patil, P. Krishnamoorthy, Mohammad Shueb, Rajan Kumar Pandey, & K. P. Suresh (2023). Comprehensive examination on codon usage bias pattern of the Bovine Ephemeral Fever Virus. Journal of Biomolecular Structure and Dynamics.
  4. Mamathashree Mandya Naganayak, Putta Kuralyanapalya Suresh, et al. (2022). A new informatics framework for evaluating the codon usage metrics, evolutionary models and phylogeographic reconstruction of Tomato Yellow Leaf Curl Virus. Int. J. Health and Allied Sciences, 11(2).
  5. Mamathashree, M. N., Prakash, B. G., Fakrudin, B., Jayashree, U., Honnabyraiah, M. K., & Mallikarjungowda, A. P. (2021). Characterization of identified distinct tamarind (Tamarindus indica L.) genotypes for yield-related morphological traits in Karnataka. Int. J. Plant & Soil Science, 33(21), 14-23.
  6. Mamathashree M. N., Fakrudin B., & Prakash B. G. (2024). Organic acid profiling in tamarind (Tamarindus indica L.) genotypes by high-performance liquid chromatography. Int. J. Adv. Biochem. Res., 8(8), 1452-1458.
  7. Mamathashree M. N., Suresh K. P., Swati Rani, Archana C. A., Yamini Sri S., Shijili M., & Mehnaj Khatoon (2024). A comprehensive immuno-informatics analysis to design and evaluate a multi-epitope vaccine against the Japanese encephalitis virus. Int. J. Adv. Biochem. Res., 8(8), 1369-1385.
  8. Mamathashree M. N., Swati Rani, Suresh K. P., Jayashree A., et al. (2024). Phytochemical profiling of Acacia nilotica against SARS-CoV-2 inhibitory potentials: Synergistic influence of the identified phytochemicals based on molecular docking. Int. J. Adv. Biochem. Res., 8(8), 1392-1407.
  9. Mamathashree, M. N., Prakash, B. G., Fakrudin, B., et al. (2020). Morphological characterization among identified distinct tamarind genotypes of Karnataka. Int. J. Curr. Microbiol. App. Sci, Spl Issue-11, 4197-4210.
  10. Mamathashree, M. N., Prakash, B. G., & Fakrudin, B. (2022). Genetic variability for biochemical parameters among identified distinct genotypes of tamarind in niche areas of Karnataka. The Pharma Innovation Journal, 11(3), 2111-2118.